BACKGROUND AND PURPOSE: Cerebellar hemangioblastomas (HBs) are traditionally classified into different morphologic types: cystic and. Hemangioblastomas (capilliary hemangioblastomas) are tumors of the central nervous system that originate from the vascular system usually during middle- age. The occurrence of cerebral hemangioblastoma in a patient with on Hippel-Lindau disease is very rare. In , Rochat described a cerebral hemangioblastoma.

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Hemangioblastomas are most commonly composed of stromal cells in small blood vessels and usually occur in the cerebellumbrain stem or spinal cord. Follow-up ranged from 0 to months in these studies.

Pathology Outlines – Hemangioblastoma

Long-term prognosis cerrbral hemangioblastomas of the central nervous system: Not infrequently the mural nodule itself has cystic spaces within it.

CNS hemangioblastomas, especially multiple hemangioblastomas, are the most common manifestation of VHL disease.

The long-term results of gamma knife radiosurgery for hemangioblastomas of the brain. Astrocytes in hemangioblastomas of the central nervous system and their relationship to stromal cells. On the basis of our analysis of the literature on published cases of supratentorial hemangioblastoma, gross-total resection appears to be superior to other treatment modalities in extending PFS. Five percent of patients underwent postsurgical treatment with fractionated radiotherapy.


Inhibin alpha distinguishes hemangioblastoma from clear cell renal cell carcinoma.

Abstract Supratentorial hemangioblastoma is a rare form of hemangioblastoma; little information is available regarding prognosis, treatment, and clinical characteristics, because the available literature is primarily composed of case reports and small case series.

Second Operation At craniotomy, a right cerebellar hemangioblastoma and cyst were identified and the tumor excised. Thus, surgery has been the mainstay treatment for CNS hemangioblastomas with good outcomes. Report of a case and review of the literature. Case 20 Case Because of the relative rarity of this tumor, this study aims to accurately describe outcome and tumor location characteristics using ferebral data set that would be difficult to accumulate at a single center treating this tumor.


Cellular and reticular variants of hemangioblastoma differ in their cytogenetic profiles. Hemangioblastomas of the central nervous system in von Hippel-Lindau syndrome and sporadic disease.

Symptomatic intrasellar hemangioblastoma in a child treated with subtotal resection and adjuvant radiosurgery. More on this topic Differences in genetic and epigenetic alterations between von Hippel—Lindau disease—related and sporadic hemangioblastomas of the central nervous system.

Role of fractionated external beam radiotherapy in hemangioblastoma of the central nervous system. Cerebellar hemangioblastomas occurred in all four men. Photomicrographs of the cerebellar hemangioblastoma, third operation left and the cerebral hemangioblastoma, fourth operation right. Summary We have reported a patient in whom a cerebral hemangioblastoma had the same gross and microscopic appearance as the several cerebellar lesions removed in preceding years.


Congenital supratentorial hemangioblastoma as an unusual cause of simultaneous supra- and infratentorial intracranial hemorrhage: Receive exclusive offers and updates from Oxford Academic.

Case 13 Case Report of two cases and review of the literature. Case 3 Case 3.

Cerebral Hemangioblastoma Occurring in a Patient with von Hippel-Lindau Disease

No consensus is currently available regarding appropriate management approaches for supratentorial hemangioblastomas or whether supratentorial hemangioblastoma is part of the stigmata of VHL. Hemangioblastomas are uncommon tumors of the central nervous system CNS that were first described by von Hippel in Supratentorial hemangoblastoma hemangioblastoma with infratentorial extension—a unique location and a rare infant case.

There were no other signs or symptoms of a cerebral neoplasm.

Comment Cerebellar hemangioblastoma, while infrequently encountered, is not rare. Patients were considered to have VHL disease if the study reported that they met clinical diagnostic criteria or genetic testing requirements.