Download scientific diagram | – Cnidoscolus quercifolius plant. from publication: Análise Química e Bromatológica da Forragem da Faveleira (Cnidoscolus. PDF | Objective: To evaluate the chemical components of active extract from Cnidoscolus quercifolius root bark and its cytotoxic potential. The Cnidoscolus quercifolius (Pohl) popularly known as “favela” or “faveleira” is a forager that is part of the native species from the caatinga.

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In Brazil, the first Europeans who settled in the land ran across a large quantity of medicinal plants used by the indigenous populations who lived here. The lethality assay against Artemia sp. The MIC was studied for bacterial strains that were sensitive to the methanolic extracts of faveleira in the agar diffusion method Table 2.

View at Google Scholar M. The results demonstrated great potential as an antimicrobial agent, an important antioxidant capacity, and acetylcholinesterase inhibition response with no significant difference compared with the reference drug. The use of less complex animal organisms, as is the case of Artemia salinacan be done to evaluate the toxicity of bioactive compounds, besides being a simple, fast, and low-cost test.

Moreover, other factors such as seasonality, circadian rhythm, development, climatic factors, water availability, ultraviolet radiation, nutrients, air pollution, and altitude may influence the composition quercirolius the secondary metabolites of plants [ 32 ]. The methodology began with the collection and herborization of the plant material, to obtain the chemical compounds, preliminary phytochemical analysis, and extraction of the constituents of the active extracts.

To analyze the significance chidoscolus the differences between the samples the authors used Variance Analysis ANOVA followed by the Newman-Keuls comparison test, being considered significant. With the aid of a light source, the hatched larvae were attracted to the lightened vessel part and were collected with a Pasteur pipette and then transferred to a beaker with saline water. As far as we know, there are no data in the literature showing the antioxidant activity of samples qusrcifolius C.

View at Google Scholar U. Free radicals have their production controlled in living organisms by a number of endogenous antioxidants compounds or are derived from diet and supplements. Related articles Cnidoscolus quercifolius Pohl. Chemical tests were performed using specific reagents, observing color changes or formation of precipitate, characteristic for each class of substances.


Cnidoscolus quercifolius – Wikiwand

For Holetz et al. In the present study, the methanolic extracts of the leaf, root, and root bark of C. For this reason, the present study focuses on the assessment of the therapeutic potential of this plant, by investigating its possible antioxidant, antimicrobial, and inhibitory activity of the acetylcholinesterase enzyme AChEas well as the toxicity of the methanolic extracts from three parts of Cnidoscolus quercifolius Pohl.

Da Planta ao MedicamentoC. Preliminary phytochemical analysis of C. The objective of this study was to assess the therapeutic potential of compounds extracted from Cnidoscolus quercifolius Pohl in preventing disease and its rational use as a herbal therapeutic tool.

Despite this unique condition, there was not enough incentive to direct local preservation botanical studies [ 8 ]. It stands out for its extraordinary drought resistance and medicinal properties. This is a different outcome from the findings of this study, for none of the methanolic extracts of the faveleira exhibited growth inhibition of fungi of the same family.

Advanced Search Users Online: One of the first AChE inhibitors used was physostigmine, an alkaloid isolated from a plant of the Leguminosae family, although this alkaloid is no longer used clinically, due to its short half-life. In many cases, the procedures of modern medicine and popular medicine are supplemental and constitute an effective form of primary health care, which may supplement the treatment usually employed in the lower income population.

Introduction The importance of medicinal plants in solving the health problems of the world is gaining more and more attention. In the agar diffusion method, the extracts showed activity against strains quercifoliuus Staphylococcus and E. Moreover, a xnidoscolus number of people are seeking traditional medicine for their primary health care. Among these is the faveleiraused in northeastern Brazil. Peixoto Sobrinho et al.

The United States and Germany rank among the biggest consumers quercifoliks natural products from Brazil. Result of inhibition of the acetylcholinesterase enzyme from methanolic extracts of C. The analysis of nuclear magnetic spectra of the active chloroform fraction revealed the presence of absorptions bands correspondent to a mixture of favelines such as neofavelanone, deoxofaveline or methyl-faveline, which structures were confirmed by ultraviolet spectra upon high-performance liquid chromatography with diode-array detection analysis.


The results suggest that cindoscolus substances present in faveleira Cnidoscolus quercifolius root bark extract have a cytotoxic potential against several tumor lines, showing a broader antitumour potential, and in addition no cnidodcolus to healthy cells. Antimicrobial assays against bacterial strains and fungi tested, using commercial drugs Chloramphenicol, Streptomycin, and Thiabendazole as a positive control, showed no growth of microorganisms. It was the start of a series of cultural intermixes that blended the knowledge brought in by the colonizers, the slaves, and the natives.

View at Google Scholar J. Studies have shown that plants used in traditional medicine have the effect of prevention and protection under conditions of oxidative stress [ 38 — 40 ]. This study did not detect alkaloids in any of the C.

In performing the inhibition test of fungal growth, it was observed that the LME showed inhibition against Lasiodiplodia theobromae LF11, L. This is an open access article distributed under the Creative Commons Attribution Licensewhich permits unrestricted cnixoscolus, distribution, and reproduction in any medium, provided the original work is properly cited.

Subscribe to Table of Contents Alerts. The bioautography method employing Ellman reagent allows for the identification of compounds capable of inhibiting acetylcholinesterase AChE in extracts, which enables a fractionation targeted quercifoliux the isolation of those compounds.

Then they performed a serial dilution of 2, at 4.

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It is important to note that this method only assists in optimizing the selection and does not eliminate, under any circumstance, the in vivo tests [ 24 cnidosclus. The extracts were subjected to phytochemical screening, following the protocols described by Mattos [ 16 ].

The caatingaan exclusively Brazilian biome, is one of the most endangered vegetation systems in the planet. In the analysis of the leaves of C.

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Materials and Methods 2. Matos, Plantas Medicinais no Brasil: Brine shrimp lethality test of the methanolic extracts from C.

The in vitro antioxidant activity of the extracts was determined using the 1,1-diphenylpicrylhydrazyl DPPH method, as previously reported by Brand-Williams et al.